Laboratory for Molecular Diagnostics
Center for Nephrology and Metabolic Disorders
The APOBEC3F gene encodes a protein of the APOBEC family. Enzymes of this family are responsible for mRNA editing. They introduce base exchanges before the protein is translated, which plays an important role in defense of viral infections and lipid metabolism.
| Clinic | Method | Carrier testing |
| Turnaround | 5 days | |
| Specimen type | genomic DNA |
| Research | Method | Genomic sequencing of the entire coding region |
| Turnaround | 25 days | |
| Specimen type | genomic DNA |
Disorders of mRNA editing
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APOBEC1
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APOBEC2
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APOBEC3A
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APOBEC3B
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APOBEC3C
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APOBEC3D
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APOBEC3F
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APOBEC3G
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APOBEC3H
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APOBEC4
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| 1. |
Jarmuz A et al. (2002) An anthropoid-specific locus of orphan C to U RNA-editing enzymes on chromosome 22. 
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| 2. |
Wiegand HL et al. (2004) A second human antiretroviral factor, APOBEC3F, is suppressed by the HIV-1 and HIV-2 Vif proteins.
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| 3. |
NCBI article NCBI 200316
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| 4. |
OMIM.ORG article Omim 608993
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| 5. |
Wikipedia article Wikipedia EN (APOBEC3F)
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