Enzyme APOBEC-3C
The APOBEC3C gene encodes a protein of the APOBEC family. Enzymes of this family are responsible for mRNA editing. They introduce base exchanges before the protein is translated, which plays an important role in defense of viral infections and lipid metabolism.
Genetests:
Related Diseases:
References:
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Harris RS et al. (2002) RNA editing enzyme APOBEC1 and some of its homologs can act as DNA mutators.
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Vartanian JP et al. (2008) Evidence for editing of human papillomavirus DNA by APOBEC3 in benign and precancerous lesions.
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3. |
Jarmuz A et al. (2002) An anthropoid-specific locus of orphan C to U RNA-editing enzymes on chromosome 22.
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4. |
Stauch B et al. (2009) Model structure of APOBEC3C reveals a binding pocket modulating ribonucleic acid interaction required for encapsidation.
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5. |
NCBI article
NCBI 27350
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6. |
OMIM.ORG article
Omim 607750
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7. |
Wikipedia article
Wikipedia EN (APOBEC3C)
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Update: Aug. 14, 2020