Congenital hyperinsulinism, nesidioblastosis is the most common cause of persistent hypoglycemia in infancy which is caused by increased insulin secretion despite of low blood glycose levels. The most important complication is cerebral damage as a result of prolonged hypoglycemia. Type 4 of the disease is caused by HADH mutations.
|Hyperinsulinemic hypoglycemia 1|
|Hyperinsulinemic hypoglycemia 2|
|Hyperinsulinemic hypoglycemia 3|
|Hyperinsulinemic hypoglycemia 4|
|Hyperinsulinemic hypoglycemia 5|
|Hyperinsulinemic hypoglycemia 6|
|Hyperinsulinemic hypoglycemia 7|
|Polycystic kidney disease with hyperinsulinemic hypoglycemia|
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Molven A et al. (2002) Hunting for a hypoglycemia gene: severe neonatal hypoglycemia in a consanguineous family.
Gotlin RW et al. (1970) Neonatal hypoglycaemia, hyperinsulinism, and absence of pancreatic alpha-cells.
OMIM.ORG articleOmim 609975