Congenital hyperinsulinism, nesidioblastosis is the most common cause of persistent hypoglycemia in infancy which is caused by increased insulin secretion despite of low blood glycose levels. The most important complication is cerebral damage as a result of prolonged hypoglycemia. Type 2 of the disease is caused by KCNJ11 mutations.
|Hyperinsulinemic hypoglycemia 1|
|Hyperinsulinemic hypoglycemia 2|
|Hyperinsulinemic hypoglycemia 3|
|Hyperinsulinemic hypoglycemia 4|
|Hyperinsulinemic hypoglycemia 5|
|Hyperinsulinemic hypoglycemia 6|
|Hyperinsulinemic hypoglycemia 7|
|Polycystic kidney disease with hyperinsulinemic hypoglycemia|
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Nestorowicz A et al. (1997) A nonsense mutation in the inward rectifier potassium channel gene, Kir6.2, is associated with familial hyperinsulinism.
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OMIM.ORG articleOmim 601820