Unter Autoimmunpolyendokrinopathie werden endokrinologische Erkrankungen zusammengefasst, die gleichzeitig mehrere Hormonsysteme betreffen können. Bei der Pathogenese spielen Autoimmunphänomene eine Rolle.
Das Autoimmun-Polyendokrinopathie-Syndrom lässt sich in 4 Typen unterteilen:
Typ 1 Chronische Candidiasis, Hypoparathyreoidismus, und autoimmun adrenale Insuffizienz (Morbus Addison) (mind. 2 vorhanden.)
Typ 2 Autoimmune adrenale Insuffizienz (Morbus Addison) und autoimmun Thyreoiditis oder Type 1 Diabetes (Mb Addison muss immer vorhanden sein.)
Typ 3 Autoimmun Thyroiditis und eine andere Autoimmunerkrankung aber kein Mb Addison.
Typ 4 Zwei oder mehr organspezifische Autoimmunerkrankungen, die nicht in die Gruppen 1-3 fallen.
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OMIM.ORG article Omim 304790 |