Laboratory for Molecular Diagnostics
Center for Nephrology and Metabolic Disorders
Moldiag Diseases Genes Support Contact

Noninsulin-dependent diabetes mellitus 1

Noninsulin-dependent diabetes mellitus can be caused by various gene mutations. The disease caused by CAPN10 mutations is a separate subgroup.

Systematic

Diabetes mellitus
Diabetic nephropathy
Diabetic retinopathy
Gestational diabetes mellitus
Hereditary susceptibility to diabetes
Insulin resistance
MODY diabetes
Mitochondrial diabetes
Neonatal diabetes mellitus
Noninsulin-dependent diabetes mellitus 1
CAPN10
Pancreatogenic diabetes
Severe obesity and type 2 diabetes
Susceptibility to type 1 diabetes 01

References:

1.

Horikawa Y et al. (2000) Genetic variation in the gene encoding calpain-10 is associated with type 2 diabetes mellitus.

external link
2.

Hanis CL et al. (1996) A genome-wide search for human non-insulin-dependent (type 2) diabetes genes reveals a major susceptibility locus on chromosome 2.

external link
3.

Altshuler D et al. (2000) Guilt by association.

external link
4.

None (2001) Challenges in identifying genetic variation affecting susceptibility to type 2 diabetes: examples from studies of the calpain-10 gene.

external link
5.

Kang ES et al. (2006) A novel 111/121 diplotype in the Calpain-10 gene is associated with type 2 diabetes.

external link
6.

Ghosh S et al. (1998) A large sample of finnish diabetic sib-pairs reveals no evidence for a non-insulin-dependent diabetes mellitus susceptibility locus at 2qter.

external link
7.

Cox NJ et al. (1999) Loci on chromosomes 2 (NIDDM1) and 15 interact to increase susceptibility to diabetes in Mexican Americans.

external link
8.

Busfield F et al. (2002) A genomewide search for type 2 diabetes-susceptibility genes in indigenous Australians.

external link
9.

OMIM.ORG article

Omim 601283 external link
Update: Aug. 14, 2020
Copyright © 2005-2021 by Center for Nephrology and Metabolic Disorders, Dr. Mato Nagel, MD
Albert-Schweitzer-Ring 32, D-02943 Weißwasser, Germany, Tel.: +49-3576-287922, Fax: +49-3576-287944
Sitemap | Webmail | Disclaimer | Privacy Issues | Website Credits