LIM/Homeobox-Protein Lhx4

Sheng HZ et al. (1996) Specification of pituitary cell lineages by the LIM homeobox gene Lhx3.

Sharma K et al. (1998) LIM homeodomain factors Lhx3 and Lhx4 assign subtype identities for motor neurons.

Machinis K et al. (2001) Syndromic short stature in patients with a germline mutation in the LIM homeobox LHX4.

Tajima T et al. (2007) A novel missense mutation (P366T) of the LHX4 gene causes severe combined pituitary hormone deficiency with pituitary hypoplasia, ectopic posterior lobe and a poorly developed sella turcica.

Pfaeffle RW et al. (2008) Three novel missense mutations within the LHX4 gene are associated with variable pituitary hormone deficiencies.

Li H et al. (1994) Gsh-4 encodes a LIM-type homeodomain, is expressed in the developing central nervous system and is required for early postnatal survival.

Yamashita T et al. (1997) Lhx4, a LIM homeobox gene.

Sheng HZ et al. (1997) Multistep control of pituitary organogenesis.

Kawamata N et al. (2002) A novel chromosomal translocation t(1;14)(q25;q32) in pre-B acute lymphoblastic leukemia involves the LIM homeodomain protein gene, Lhx4.

Castinetti F et al. (2008) A novel dysfunctional LHX4 mutation with high phenotypical variability in patients with hypopituitarism.

Orphanet article

NCBI article

OMIM.ORG article