Micro RNA miRNA33B
The MIR33B gene encodes a micro-RNA that is not translated but involved in gene regulation. Epigenetic modification of this gene was associated with dyslipidemia.
Genetests:
Related Diseases:
References:
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Najafi-Shoushtari SH et al. (2010) MicroRNA-33 and the SREBP host genes cooperate to control cholesterol homeostasis.
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2. |
Braun KV et al. (2016) The role of DNA methylation in dyslipidaemia: A systematic review.
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3. |
Pfeiffer L et al. (2015) DNA methylation of lipid-related genes affects blood lipid levels.
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4. |
Rayner KJ et al. (2011) Inhibition of miR-33a/b in non-human primates raises plasma HDL and lowers VLDL triglycerides.
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5. |
Griffiths-Jones S et al. (2006) miRBase: microRNA sequences, targets and gene nomenclature.
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6. |
Brown MS et al. (2010) Medicine. HDL miR-ed down by SREBP introns.
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7. |
NCBI article
NCBI 693120
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8. |
OMIM.ORG article
Omim 613486
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Update: Aug. 14, 2020