Oxidative stress-responsive 1 protein
The gene product is a serine-threonine kinase that plays a role in response to oxidative stress. It may also have a role in signal transduction downstream from WNK kinases to SLC12A cotransporters.
Genetests:
Related Diseases:
References:
1. |
Daigo Y et al. (1999) Characterization of a 1200-kb genomic segment of chromosome 3p22-p21.3.
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2. |
Tamari M et al. (1999) Isolation and characterization of a novel serine threonine kinase gene on chromosome 3p22-21.3.
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3. |
Chen W et al. (2004) Characterization of OSR1, a member of the mammalian Ste20p/germinal center kinase subfamily.
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4. |
Anselmo AN et al. (2006) WNK1 and OSR1 regulate the Na+, K+, 2Cl- cotransporter in HeLa cells.
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5. |
NCBI article
NCBI 9943
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6. |
OMIM.ORG article
Omim 604046
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7. |
Wikipedia article
Wikipedia EN (OXSR1)
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Update: Aug. 14, 2020