Laboratory for Molecular Diagnostics
Center for Nephrology and Metabolic Disorders
The gene KLF11 encodes a zinc finger transcription factor involved in regulation of insulin secretetion. Missensemutations in this gene might cause autosomal dominant MODY7 diabetes.
| Clinic | Method | Carrier testing |
| Turnaround | 5 days | |
| Specimen type | genomic DNA |
| Clinic | Method | Massive parallel sequencing |
| Turnaround | 25 days | |
| Specimen type | genomic DNA |
| Clinic | Method | Genomic sequencing of the entire coding region |
| Turnaround | 25 days | |
| Specimen type | genomic DNA |
| Clinic | Method | Multiplex Ligation-Dependent Probe Amplification |
| Turnaround | 25 days | |
| Specimen type | genomic DNA |
| 1. |
Neve B et al. (2005) Role of transcription factor KLF11 and its diabetes-associated gene variants in pancreatic beta cell function. 
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| 2. |
NCBI article NCBI 8462
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| 3. |
OMIM.ORG article Omim 603301
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| 4. |
Orphanet article Orphanet ID 122868
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| 5. |
Wikipedia article Wikipedia EN (KLF11)
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