Alanine-glyoxylate aminotransferase
The enzyme Alanine-glyoxylate aminotransferase is located in liver peroxisomes. In hyperoxaluria type 1 (oxalosis 1), its activity in liver cells is significantly reduced.
Genetests:
Related Diseases:
References:
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Purdue PE et al. (1990) Identification of mutations associated with peroxisome-to-mitochondrion mistargeting of alanine/glyoxylate aminotransferase in primary hyperoxaluria type 1.
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Orphanet article
Orphanet ID 119538
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NCBI article
NCBI 189
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OMIM.ORG article
Omim 604285
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Wikipedia article
Wikipedia EN (AGXT)
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Update: Aug. 14, 2020