The risk of diabetic microvascular complications can be conditioned by genetic variants in the IL1RN gene which encodes an interleukin 1.
1. |
Blakemore AI et. al. (1996) Interleukin-1 receptor antagonist allele (IL1RN*2) associated with nephropathy in diabetes mellitus. |
2. |
Lee SH et. al. () Polymorphisms in interleukin-1 beta and Interleukin-1 receptor antagonist genes are associated with kidney failure in Korean patients with type 2 diabetes mellitus. |