HIV1 susceptibility

He W et al. (2008) Duffy antigen receptor for chemokines mediates trans-infection of HIV-1 from red blood cells to target cells and affects HIV-AIDS susceptibility.

Gao X et al. (2005) AIDS restriction HLA allotypes target distinct intervals of HIV-1 pathogenesis.

Granelli-Piperno A et al. (2006) HIV-1 selectively infects a subset of nonmaturing BDCA1-positive dendritic cells in human blood.

Schindler M et al. (2006) Nef-mediated suppression of T cell activation was lost in a lentiviral lineage that gave rise to HIV-1.

Jennes W et al. (2006) Cutting edge: resistance to HIV-1 infection among African female sex workers is associated with inhibitory KIR in the absence of their HLA ligands.

Wilkin TJ et al. (2007) HIV type 1 chemokine coreceptor use among antiretroviral-experienced patients screened for a clinical trial of a CCR5 inhibitor: AIDS Clinical Trial Group A5211.

Zhou T et al. (2007) Structural definition of a conserved neutralization epitope on HIV-1 gp120.

Hladik F et al. (2007) Initial events in establishing vaginal entry and infection by human immunodeficiency virus type-1.

Triboulet R et al. (2007) Suppression of microRNA-silencing pathway by HIV-1 during virus replication.

Gulick RM et al. (2007) Phase 2 study of the safety and efficacy of vicriviroc, a CCR5 inhibitor, in HIV-1-Infected, treatment-experienced patients: AIDS clinical trials group 5211.

Jiménez-Baranda S et al. (2007) Filamin-A regulates actin-dependent clustering of HIV receptors.

Fellay J et al. (2007) A whole-genome association study of major determinants for host control of HIV-1.

Huang J et al. (2007) Cellular microRNAs contribute to HIV-1 latency in resting primary CD4+ T lymphocytes.

Brass AL et al. (2008) Identification of host proteins required for HIV infection through a functional genomic screen.

Burt TD et al. (2008) Apolipoprotein (apo) E4 enhances HIV-1 cell entry in vitro, and the APOE epsilon4/epsilon4 genotype accelerates HIV disease progression.

Soriano A et al. (2005) Polymorphisms in the interleukin-4 receptor alpha chain gene influence susceptibility to HIV-1 infection and its progression to AIDS.

Mandl JN et al. (2008) Divergent TLR7 and TLR9 signaling and type I interferon production distinguish pathogenic and nonpathogenic AIDS virus infections.

Kulkarni H et al. (2009) The Duffy-null state is associated with a survival advantage in leukopenic HIV-infected persons of African ancestry.

Manganaro L et al. (2010) Concerted action of cellular JNK and Pin1 restricts HIV-1 genome integration to activated CD4+ T lymphocytes.

Kosmrlj A et al. (2010) Effects of thymic selection of the T-cell repertoire on HLA class I-associated control of HIV infection.

Cagliani R et al. (2010) Genetic diversity at endoplasmic reticulum aminopeptidases is maintained by balancing selection and is associated with natural resistance to HIV-1 infection.

Zhang W et al. (2011) T-cell differentiation factor CBF-β regulates HIV-1 Vif-mediated evasion of host restriction.

Jäger S et al. (2011) Vif hijacks CBF-β to degrade APOBEC3G and promote HIV-1 infection.

Richardson MW et al. (2012) Kruppel-like factor 2 modulates CCR5 expression and susceptibility to HIV-1 infection.

Harman AN et al. (2015) HIV Blocks Interferon Induction in Human Dendritic Cells and Macrophages by Dysregulation of TBK1.

Yoh SM et al. (2015) PQBP1 Is a Proximal Sensor of the cGAS-Dependent Innate Response to HIV-1.

Sperandio S et al. (2015) TOE1 is an inhibitor of HIV-1 replication with cell-penetrating capability.

Usami Y et al. (2015) SERINC3 and SERINC5 restrict HIV-1 infectivity and are counteracted by Nef.

Rosa A et al. (2015) HIV-1 Nef promotes infection by excluding SERINC5 from virion incorporation.

Ramsuran V et al. (2018) Elevated expression impairs HIV control through inhibition of NKG2A-expressing cells.

Liu H et al. (1999) Polymorphism in RANTES chemokine promoter affects HIV-1 disease progression.

Rosenwasser LJ et. al. (1997) Genetics of atopy and asthma: the rationale behind promoter-based candidate gene studies (IL-4 and IL-10).

Shin HD et. al. (2000) Genetic restriction of HIV-1 pathogenesis to AIDS by promoter alleles of IL10.

Carrington M et al. (1999) HLA and HIV-1: heterozygote advantage and B*35-Cw*04 disadvantage.

Thomas R et al. (2009) HLA-C cell surface expression and control of HIV/AIDS correlate with a variant upstream of HLA-C.

Vasilescu A et al. (2007) A haplotype of the human CXCR1 gene protective against rapid disease progression in HIV-1+ patients.

An P et al. (2003) A tumor necrosis factor-alpha-inducible promoter variant of interferon-gamma accelerates CD4+ T cell depletion in human immunodeficiency virus-1-infected individuals.

Sironi M et al. (2012) A common polymorphism in TLR3 confers natural resistance to HIV-1 infection.

Yan N et al. (2010) The cytosolic exonuclease TREX1 inhibits the innate immune response to human immunodeficiency virus type 1.

Samson M et al. (1996) Resistance to HIV-1 infection in caucasian individuals bearing mutant alleles of the CCR-5 chemokine receptor gene.

Liu R et al. (1996) Homozygous defect in HIV-1 coreceptor accounts for resistance of some multiply-exposed individuals to HIV-1 infection.

Dean M et al. (1996) Genetic restriction of HIV-1 infection and progression to AIDS by a deletion allele of the CKR5 structural gene. Hemophilia Growth and Development Study, Multicenter AIDS Cohort Study, Multicenter Hemophilia Cohort Study, San Francisco City Cohort, ALIVE Study.

Smith MW et al. (1997) Contrasting genetic influence of CCR2 and CCR5 variants on HIV-1 infection and disease progression. Hemophilia Growth and Development Study (HGDS), Multicenter AIDS Cohort Study (MACS), Multicenter Hemophilia Cohort Study (MHCS), San Francisco City Cohort (SFCC), ALIVE Study.

Winkler C et al. (1998) Genetic restriction of AIDS pathogenesis by an SDF-1 chemokine gene variant. ALIVE Study, Hemophilia Growth and Development Study (HGDS), Multicenter AIDS Cohort Study (MACS), Multicenter Hemophilia Cohort Study (MHCS), San Francisco City Cohort (SFCC)

Martin MP et al. (1998) Genetic acceleration of AIDS progression by a promoter variant of CCR5.

Cressey TR et al. (2007) Pharmacogenetics of antiretroviral drugs for the treatment of HIV-infected patients: an update.

Migueles SA et al. (2000) HLA B*5701 is highly associated with restriction of virus replication in a subgroup of HIV-infected long term nonprogressors.

Faure S et al. (2000) Rapid progression to AIDS in HIV+ individuals with a structural variant of the chemokine receptor CX3CR1.

Gao X et al. (2001) Effect of a single amino acid change in MHC class I molecules on the rate of progression to AIDS.

An P et al. (2002) Modulating influence on HIV/AIDS by interacting RANTES gene variants.

Martin MP et al. (2002) Epistatic interaction between KIR3DS1 and HLA-B delays the progression to AIDS.

Modi WS et al. (2003) MCP-1-MCP-3-Eotaxin gene cluster influences HIV-1 transmission.

O'Brien SJ et al. (2004) Human genes that limit AIDS.

Nolan D et al. (2004) Impact of host genetics on HIV disease progression and treatment: new conflicts on an ancient battleground.

None (2004) HIV-host interactions: vital to the virus and key to its inhibition.

Lassen K et al. (2004) The multifactorial nature of HIV-1 latency.

Martin MP et al. (2004) Association of DC-SIGN promoter polymorphism with increased risk for parenteral, but not mucosal, acquisition of human immunodeficiency virus type 1 infection.

Kaslow RA et al. (2005) Influence of host genetic variation on susceptibility to HIV type 1 infection.

Gonzalez E et al. (2005) The influence of CCL3L1 gene-containing segmental duplications on HIV-1/AIDS susceptibility.

Colobran R et al. (2005) Multiple products derived from two CCL4 loci: high incidence of a new polymorphism in HIV+ patients.