Familial gestational hyperthyroidism is an autosomal dominant disorder caused by activating mutations of the TSHR gene.
Hyperthyroidism | ||||
Familial gestational hyperthyroidism | ||||
TSHR | ||||
Graves disease | ||||
McCune-Albright syndrom | ||||
Non-autoimmune hyperthyroidism | ||||
Susceptibility to thyrotoxic periodic paralysis 1 | ||||
1. |
Rodien P et al. (1998) Familial gestational hyperthyroidism caused by a mutant thyrotropin receptor hypersensitive to human chorionic gonadotropin. |
2. |
Grossmann M et al. (1997) Novel insights into the molecular mechanisms of human thyrotropin action: structural, physiological, and therapeutic implications for the glycoprotein hormone family. |
3. |
OMIM.ORG article Omim 603373 |
4. |
Orphanet article Orphanet ID 99819 |