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IgA nephropathy type 1

IgA nephropathy type 1 is a probably autosomal dominant disorder associated with genetic alterations at chromosome position 6q22-q23. The exact gene is not yet discovered.

Systematic

IgA nephropathy
CFHR1
CFHR3
CFHR5
IgA nephropathy type 1
IgA nephropathy type 2
IgA nephropathy type 3

References:

1.

Brettle R et al. (1978) Mesangial IgA glomerulonephritis and HLA antigens.

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2.

Pei Y et al. (1997) Association of angiotensinogen gene T235 variant with progression of immunoglobin A nephropathy in Caucasian patients.

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3.

Julian BA et al. (1985) Familial IgA nephropathy. Evidence of an inherited mechanism of disease.

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4.

Jennette JC et al. (1985) Low incidence of IgA nephropathy in blacks.

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5.

None (1969) IgA glomerular deposits in renal disease.

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6.

Sabatier JC et al. (1979) Mesangial IgA glomerulonephritis in HLA-identical brothers.

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7.

McCoy RC et al. (1974) IgA nephropathy.

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8.

Croker BP et al. (1983) IgA nephropathy. Correlation of clinical and histologic features.

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9.

Bene MC et al. (1983) Immunoglobulin A nephropathy. Quantitative immunohistomorphometry of the tonsillar plasma cells evidences an inversion of the immunoglobulin A versus immunoglobulin G secreting cell balance.

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10.

Berthoux FC et al. (1978) HLA-Bw35 and mesangial IgA glomerulonephritis.

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11.

Coppo R et al. (1986) Dietary gluten and primary IgA nephropathy.

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12.

Tolkoff-Rubin NE et al. (1978) IGA nephropathy in HLA-identical siblings.

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13.

Katz A et al. (1980) Family study in IgA nephritis: the possible role of HLA antigens.

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14.

Tomana M et al. (1997) Galactose-deficient IgA1 in sera of IgA nephropathy patients is present in complexes with IgG.

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15.

Shimokawa T et al. (2000) Identification and characterization of the promoter for the gene encoding the human myeloid IgA Fc receptor (FcalphaR, CD89).

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16.

Tsuge T et al. (2001) Polymorphism in promoter region of Fcalpha receptor gene in patients with IgA nephropathy.

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17.

Obara W et al. (2003) Association of single-nucleotide polymorphisms in the polymeric immunoglobulin receptor gene with immunoglobulin A nephropathy (IgAN) in Japanese patients.

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18.

Paterson AD et al. (2007) Genome-wide linkage scan of a large family with IgA nephropathy localizes a novel susceptibility locus to chromosome 2q36.

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19.

Gharavi AG et al. (2011) Genome-wide association study identifies susceptibility loci for IgA nephropathy.

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20.

Wyatt RJ et al. (2013) IgA nephropathy.

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21.

Takei T et al. (2002) Association between single-nucleotide polymorphisms in selectin genes and immunoglobulin A nephropathy.

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22.

Yoshida H et al. (1995) Role of the deletion of polymorphism of the angiotensin converting enzyme gene in the progression and therapeutic responsiveness of IgA nephropathy.

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23.

Song J et al. (2003) Peroxisome proliferator-activated receptor gamma C161T polymorphisms and survival of Japanese patients with immunoglobulin A nephropathy.

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24.

Scolari F et al. (1999) Familial clustering of IgA nephropathy: further evidence in an Italian population.

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25.

Zheng F et al. (1999) Uteroglobin is essential in preventing immunoglobulin A nephropathy in mice.

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26.

Hsu SI et al. (2000) Evidence for genetic factors in the development and progression of IgA nephropathy.

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27.

Gharavi AG et al. (2000) IgA nephropathy, the most common cause of glomerulonephritis, is linked to 6q22-23.

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28.

Hiki Y et al. (2001) Mass spectrometry proves under-O-glycosylation of glomerular IgA1 in IgA nephropathy.

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29.

Allen AC et al. (2001) Mesangial IgA1 in IgA nephropathy exhibits aberrant O-glycosylation: observations in three patients.

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30.

Asamoah A et al. (1987) A major gene model for the familial aggregation of plasma IgA concentration.

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31.

Donadio JV et al. (2002) IgA nephropathy.

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32.

Yoon HJ et al. (2003) Association of the CD14 gene -159C polymorphism with progression of IgA nephropathy.

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33.

Song J et al. (2003) Gender specific association of aldosterone synthase gene polymorphism with renal survival in patients with IgA nephropathy.

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34.

Wang J et al. (2004) Dysregulated LIGHT expression on T cells mediates intestinal inflammation and contributes to IgA nephropathy.

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35.

Bisceglia L et al. (2006) Genetic heterogeneity in Italian families with IgA nephropathy: suggestive linkage for two novel IgA nephropathy loci.

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36.

Suzuki H et al. (2008) IgA1-secreting cell lines from patients with IgA nephropathy produce aberrantly glycosylated IgA1.

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37.

None (1989) Familial cases of Berger's disease and anaphylactoid purpura: more frequent than previously thought.

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38.

None (1987) The commonest glomerulonephritis in the world: IgA nephropathy.

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39.

Julian BA et al. (1988) IgA nephropathy, the most common glomerulonephritis worldwide. A neglected disease in the United States?

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40.

OMIM.ORG article

Omim 161950 external link
Update: Aug. 14, 2020
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