Open angle glaucoma 1M is a disease that manifests in early adulthood. Although hereditary its genetic cause is not completely discovered. Genetic localization is the 5q22.1-q32 chromosomal region.
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Wang DY et al. (2004) Absence of myocilin and optineurin mutations in a large Philippine family with juvenile onset primary open angle glaucoma. |
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Pang CP et al. (2006) A genome-wide scan maps a novel juvenile-onset primary open angle glaucoma locus to chromosome 5q. |
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Fan BJ et al. (2007) Fine mapping of new glaucoma locus GLC1M and exclusion of neuregulin 2 as the causative gene. |
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OMIM.ORG article Omim 610535 |