IL17F-Gen
Das IL17F-Gen kodiert das Zytokin Interleukin 17F. Dieses wird von aktivierten T-Lymphozyten gebildet und ist in der Immunregulation involviert. Mutationen verursachen Candidose 6.
Gentests:
Klinisch |
Untersuchungsmethoden |
Familienuntersuchung |
Bearbeitungszeit |
5 Tage |
Probentyp |
genomische DNS |
Verknüpfte Erkrankungen:
Referenzen:
1. |
McAllister F et al. (2005) Role of IL-17A, IL-17F, and the IL-17 receptor in regulating growth-related oncogene-alpha and granulocyte colony-stimulating factor in bronchial epithelium: implications for airway inflammation in cystic fibrosis.
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2. |
Toy D et al. (2006) Cutting edge: interleukin 17 signals through a heteromeric receptor complex.
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3. |
Kudva A et al. (2011) Influenza A inhibits Th17-mediated host defense against bacterial pneumonia in mice.
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4. |
Puel A et al. (2011) Chronic mucocutaneous candidiasis in humans with inborn errors of interleukin-17 immunity.
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5. |
Starnes T et al. (2001) Cutting edge: IL-17F, a novel cytokine selectively expressed in activated T cells and monocytes, regulates angiogenesis and endothelial cell cytokine production.
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6. |
Kawaguchi M et al. (2001) Identification of a novel cytokine, ML-1, and its expression in subjects with asthma.
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7. |
Hurst SD et al. (2002) New IL-17 family members promote Th1 or Th2 responses in the lung: in vivo function of the novel cytokine IL-25.
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8. |
Wang X et al. (2012) Transcription of Il17 and Il17f is controlled by conserved noncoding sequence 2.
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Update: 14. August 2020