Glypican-3

Pilia G et al. (1996) Mutations in GPC3, a glypican gene, cause the Simpson-Golabi-Behmel overgrowth syndrome.

Maurel M et al. (2013) MicroRNA-1291-mediated silencing of IRE1α enhances Glypican-3 expression.

Shi W et al. (2009) A patient with the Simpson-Golabi-Behmel syndrome displays a loss-of-function point mutation in GPC3 that inhibits the attachment of this proteoglycan to the cell surface.

Filmus J et al. (2008) Glypicans.

Capurro MI et al. (2008) Glypican-3 inhibits Hedgehog signaling during development by competing with patched for Hedgehog binding.

Veugelers M et al. (2000) Mutational analysis of the GPC3/GPC4 glypican gene cluster on Xq26 in patients with Simpson-Golabi-Behmel syndrome: identification of loss-of-function mutations in the GPC3 gene.

Lindsay S et al. (1997) Large scale deletions in the GPC3 gene may account for a minority of cases of Simpson-Golabi-Behmel syndrome.

Shen T et al. (1997) Mapping of the Simpson-Golabi-Behmel overgrowth syndrome gene (GPC3) to chromosome X in human and rat by fluorescence in situ hybridization.

Hughes-Benzie RM et al. (1996) Simpson-Golabi-Behmel syndrome: genotype/phenotype analysis of 18 affected males from 7 unrelated families.

Filmus J et al. (1995) Identification of a new membrane-bound heparan sulphate proteoglycan.

Filmus J et al. (1988) Isolation of a cDNA corresponding to a developmentally regulated transcript in rat intestine.

White GR et al. (2002) Somatic glypican 3 (GPC3) mutations in Wilms' tumour.

Pénisson-Besnier I et al. (2008) Carotid artery dissection in an adult with the Simpson-Golabi-Behmel syndrome.

Romanelli V et al. (2007) Germinal mosaicism in Simpson-Golabi-Behmel syndrome.

Sakazume S et al. (2007) GPC3 mutations in seven patients with Simpson-Golabi-Behmel syndrome.

Rodríguez-Criado G et al. (2005) Clinical and molecular studies on two further families with Simpson-Golabi-Behmel syndrome.

Xuan JY et al. (1999) A small interstitial deletion in the GPC3 gene causes Simpson-Golabi-Behmel syndrome in a Dutch-Canadian family.

Sood R et al. (2006) Gene expression patterns in human placenta.

NCBI article

OMIM.ORG article

Orphanet article