Thyrotropin-Releasing-Hormon (TRH)
Durch das TRH-Gen wird das Thyrotropin-Releasing-Hormon kodiert. Mutationen führen zur autosomal rezessiven hypothalamischen Hypothyreose.
Gentests:
Klinisch |
Untersuchungsmethoden |
Familienuntersuchung |
Bearbeitungszeit |
5 Tage |
Probentyp |
genomische DNS |
Verknüpfte Erkrankungen:
Referenzen:
1. |
Krashes MJ et al. (2014) An excitatory paraventricular nucleus to AgRP neuron circuit that drives hunger.
|
2. |
Yamada M et al. (1991) Assignment of human preprothyrotropin-releasing hormone (TRH) gene to chromosome 3.
|
3. |
Yamada M et al. (1990) Cloning and structure of human genomic DNA and hypothalamic cDNA encoding human prepro thyrotropin-releasing hormone.
|
4. |
Roller ML et al. (1995) Localization of the thyrotropin-releasing hormone gene, Trh, on mouse chromosome 6.
|
5. |
Yamada M et al. (1999) Assignment of the thyrotropin-releasing hormone gene (TRH) to human chromosome 3q13.3-->q21 by in situ hybridization.
|
6. |
Gáspár E et al. (2010) Thyrotropin releasing hormone (TRH): a new player in human hair-growth control.
|
7. |
NCBI article
NCBI 7200
|
8. |
OMIM.ORG article
Omim 613879
|
9. |
Orphanet article
Orphanet ID 120259
|
10. |
Wikipedia Artikel
Wikipedia DE (Thyreoliberin)
|
Update: 14. August 2020