Zyklisches-cAMP-abhängiger Transkriptionsfaktor 6 alpha

Hai TW et al. (1989) Transcription factor ATF cDNA clones: an extensive family of leucine zipper proteins able to selectively form DNA-binding heterodimers.

Meex SJ et al. (2009) The ATF6-Met[67]Val substitution is associated with increased plasma cholesterol levels.

Ansar M et al. (2015) Mutation of ATF6 causes autosomal recessive achromatopsia.

Kohl S et al. (2015) Mutations in the unfolded protein response regulator ATF6 cause the cone dysfunction disorder achromatopsia.

Higa A et al. (2014) Endoplasmic reticulum stress-activated transcription factor ATF6α requires the disulfide isomerase PDIA5 to modulate chemoresistance.

Meex SJ et al. (2007) Activating transcription factor 6 polymorphisms and haplotypes are associated with impaired glucose homeostasis and type 2 diabetes in Dutch Caucasians.

Thameem F et al. (2006) Association of amino acid variants in the activating transcription factor 6 gene (ATF6) on 1q21-q23 with type 2 diabetes in Pima Indians.

Shen J et al. (2002) ER stress regulation of ATF6 localization by dissociation of BiP/GRP78 binding and unmasking of Golgi localization signals.

Sommer T et al. (2002) BiP binding keeps ATF6 at bay.

Ye J et al. (2000) ER stress induces cleavage of membrane-bound ATF6 by the same proteases that process SREBPs.

Li M et al. (2000) ATF6 as a transcription activator of the endoplasmic reticulum stress element: thapsigargin stress-induced changes and synergistic interactions with NF-Y and YY1.

Haze K et al. (1999) Mammalian transcription factor ATF6 is synthesized as a transmembrane protein and activated by proteolysis in response to endoplasmic reticulum stress.

Yoshida H et al. (1998) Identification of the cis-acting endoplasmic reticulum stress response element responsible for transcriptional induction of mammalian glucose-regulated proteins. Involvement of basic leucine zipper transcription factors.

Zhu C et al. (1997) Interaction of ATF6 and serum response factor.

Lin JH et al. (2007) IRE1 signaling affects cell fate during the unfolded protein response.

Orphanet article

NCBI article

OMIM.ORG article