Glutamate/Aspartate transporter 3

Peghini P et al. (1997) Glutamate transporter EAAC-1-deficient mice develop dicarboxylic aminoaciduria and behavioral abnormalities but no neurodegeneration.

Bailey CG et al. (2011) Loss-of-function mutations in the glutamate transporter SLC1A1 cause human dicarboxylic aminoaciduria.

Kanai Y et al. (1992) Primary structure and functional characterization of a high-affinity glutamate transporter.

Smith CP et al. (1994) Assignment of the gene coding for the human high-affinity glutamate transporter EAAC1 to 9p24: potential role in dicarboxylic aminoaciduria and neurodegenerative disorders.

Lin CI et al. (2001) Modulation of the neuronal glutamate transporter EAAC1 by the interacting protein GTRAP3-18.

Aoyama K et al. (2006) Neuronal glutathione deficiency and age-dependent neurodegeneration in the EAAC1 deficient mouse.

Berman AE et al. (2011) N-acetylcysteine prevents loss of dopaminergic neurons in the EAAC1-/- mouse.

Melhem N et al. (2011) Copy number variants for schizophrenia and related psychotic disorders in Oceanic Palau: risk and transmission in extended pedigrees.

Myles-Worsley M et al. (2013) Deletion at the SLC1A1 glutamate transporter gene co-segregates with schizophrenia and bipolar schizoaffective disorder in a 5-generation family.

Orphanet article

NCBI article

OMIM.ORG article