Die genetisch bedingte Anfälligkeit gegenüber Pneumokokken Infektionen Typ 3 ist durch Variationen im TIRAP-Gen determiniert.
Invasive Pneumokokken-Erkrankung | ||||
Invasive Pneumokokken-Erkrankung 1 | ||||
Invasive Pneumokokken-Erkrankung 2 | ||||
Invasive Pneumokokken-Erkrankung 3 | ||||
TIRAP | ||||
1. |
Ku CL et al. (2007) IRAK4 and NEMO mutations in otherwise healthy children with recurrent invasive pneumococcal disease. |
2. |
Khor CC et al. (2007) A Mal functional variant is associated with protection against invasive pneumococcal disease, bacteremia, malaria and tuberculosis. |