Die Präeklampsie 1 ist eine Erkrankung der Schwangerschaft. Nach der 20. Schwangerschaftswoche kommt es es zu einem Blutdruckanstieg und zu einer Proteinurie. Im weiteren Verlauf kann sich die Erkrankung in eine lebensbedrohliche Situation (Eklampsie) entwickeln. Die Vererbung ist dominant aber das verantwortliche Gen noch unbekannt. Als Lokus wurde 2p13 in einer isländischen Studie identifiziert.
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OMIM.ORG article Omim 189800 |