Lp(a) Hyperlipoproteinämie

McCormick SP et al. (1995) Mutagenesis of the human apolipoprotein B gene in a yeast artificial chromosome reveals the site of attachment for apolipoprotein(a).

Utermann G et al. (1988) Genetics of the quantitative Lp(a) lipoprotein trait. II. Inheritance of Lp(a) glycoprotein phenotypes.

Utermann G et al. (1987) Lp(a) glycoprotein phenotypes. Inheritance and relation to Lp(a)-lipoprotein concentrations in plasma.

Weitkamp LR et al. (1988) Linkage between the loci for the Lp(a) lipoprotein (LP) and plasminogen (PLG).

None (1988) Lipoprotein(a): a genetically determined lipoprotein containing a glycoprotein of the plasminogen family.

Drayna DT et al. (1988) Genetic linkage between lipoprotein(a) phenotype and a DNA polymorphism in the plasminogen gene.

Greger V et al. (1988) No evidence for linkage between lipoprotein(a) (LPA) and esterase D (ESD).

Frank SL et al. (1988) The apolipoprotein(a) gene resides on human chromosome 6q26-27, in close proximity to the homologous gene for plasminogen.

McLean JW et al. () cDNA sequence of human apolipoprotein(a) is homologous to plasminogen.

Hasstedt SJ et al. (1983) The genetics of quantitative plasma Lp(a): analysis of a large pedigree.

Hewitt D et al. (1982) The inheritance of sinking-pre-beta lipoprotein and its relation to the Lp(a) antigen.

Ott J et al. (1982) Epistatic association and linkage analysis in human families.

Breckenridge WC et al. (1981) Quantification of sinking pre beta lipoprotein in human plasma.

Ogorelkova M et al. (1999) Molecular basis of congenital lp(a) deficiency: a frequent apo(a) 'null' mutation in caucasians.

None (1995) Characterization of the apolipoprotein(a) gene.

Ichinose A et al. (1995) Detection of polymorphisms in the 5'-flanking region of the gene for apolipoprotein(a).

Grainger DJ et al. (1994) Activation of transforming growth factor-beta is inhibited in transgenic apolipoprotein(a) mice.

Knapp RG et al. (1993) Serum lipoprotein(a) levels in elderly black and white men in the Charleston Heart Study.

Lackner C et al. (1993) Molecular definition of the extreme size polymorphism in apolipoprotein(a).

Marcovina SM et al. (1993) Identification of 34 apolipoprotein(a) isoforms: differential expression of apolipoprotein(a) alleles between American blacks and whites.

Mancini FP et al. (1995) Sequence microheterogeneity in apolipoprotein(a) gene repeats and the relationship to plasma Lp(a) levels.

Namboodiri KK et al. (1977) Linkage relationships of Lp and Ag serum lipoproteins with 25 polymorphic markers.

Suzuki K et al. (1997) Plasma lipoprotein(a) levels and expression of the apolipoprotein(a) gene are dependent on the nucleotide polymorphisms in its 5'-flanking region.

Nowak-Göttl U et al. (1997) Lipoprotein (a): its role in childhood thromboembolism.

Lou XJ et al. (1998) Fibrinogen deficiency reduces vascular accumulation of apolipoprotein(a) and development of atherosclerosis in apolipoprotein(a) transgenic mice.

None (1989) The mysteries of lipoprotein(a).

Debus O et al. (1998) Factor V Leiden and genetic defects of thrombophilia in childhood porencephaly.

Ogorelkova M et al. (2001) Single nucleotide polymorphisms in exons of the apo(a) kringles IV types 6 to 10 domain affect Lp(a) plasma concentrations and have different patterns in Africans and Caucasians.

Caplice NM et al. (2001) Lipoprotein (a) binds and inactivates tissue factor pathway inhibitor: a novel link between lipoproteins and thrombosis.

Dahlén G et al. (1976) Further evidence for the existence of genetically determined metabolic differences between Lp(a+) and Lp(a-) individuals.

Boerwinkle E et al. (1992) Apolipoprotein(a) gene accounts for greater than 90% of the variation in plasma lipoprotein(a) concentrations.

BERG K et al. (1963) GENETICS OF THE LP SYSTEM.

Malgaretti N et al. (1992) Characterization by yeast artificial chromosome cloning of the linked apolipoprotein(a) and plasminogen genes and identification of the apolipoprotein(a) 5' flanking region.

None (2003) Lp(a) lipoprotein--coping with heterogeneity.

Ariyo AA et al. (2003) Lp(a) lipoprotein, vascular disease, and mortality in the elderly.

Lawn RM et al. (1992) Atherogenesis in transgenic mice expressing human apolipoprotein(a)

Parson W et al. (2004) A common nonsense mutation in the repetitive Kringle IV-2 domain of human apolipoprotein(a) results in a truncated protein and low plasma Lp(a).

Schmidt K et al. (2006) Genetics of the Lp(a)/apo(a) system in an autochthonous Black African population from the Gabon.

Gavish D et al. (1991) Lipoprotein(a) reduction by N-acetylcysteine.

Chretien JP et al. (2006) Three single-nucleotide polymorphisms in LPA account for most of the increase in lipoprotein(a) level elevation in African Americans compared with European Americans.

VandeBerg JL et al. (1991) Linkage of plasminogen (PLG) and apolipoprotein(a) (LPA) in baboons.

López S et al. (2008) Genome-wide linkage analysis for identifying quantitative trait loci involved in the regulation of lipoprotein a (Lpa) levels.

Kamboh MI et al. (1991) Expressed hypervariable polymorphism of apolipoprotein (a).

Kondo I et al. (1990) Inherited quantitative DNA variation in the LPA ("apolipoprotein (a)") gene.

Clarke R et al. (2009) Genetic variants associated with Lp(a) lipoprotein level and coronary disease.

Sandholzer C et al. (1991) Effects of the apolipoprotein(a) size polymorphism on the lipoprotein(a) concentration in 7 ethnic groups.

Rath M et al. (1990) Hypothesis: lipoprotein(a) is a surrogate for ascorbate.

Berg K et al. (1979) Lp(a) phenotypes, other lipoprotein parameters, and a family history of coronary heart disease in middle-aged males.

Lindahl G et al. (1989) The gene for the Lp(a)-specific glycoprotein is closely linked to the gene for plasminogen on chromosome 6.

Gavish D et al. (1989) Plasma Ip(a) concentration is inversely correlated with the ratio of Kringle IV/Kringle V encoding domains in the apo(a) gene.

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