CCAAT/Enhancer-binding protein
The gene encoding an important myeloid transcription factor is mutated in cells of acute myeloid leukemia (somatic mutation) and in patients with autosomal dominant familial acute myeloid leukemia (germline mutation).
Genetests:
Related Diseases:
References:
1. |
Smith ML et al. (2004) Mutation of CEBPA in familial acute myeloid leukemia.
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2. |
Barjesteh van Waalwijk van Doorn-Khosrovani S et al. (2003) Biallelic mutations in the CEBPA gene and low CEBPA expression levels as prognostic markers in intermediate-risk AML.
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3. |
NCBI article
NCBI 1050
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4. |
OMIM.ORG article
Omim 116897
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5. |
Orphanet article
Orphanet ID 233165
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6. |
Wikipedia article
Wikipedia EN (CEBPA)
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Update: Aug. 14, 2020