Enzyme APOBEC-3H
The APOBEC3H gene encodes a protein of the APOBEC family. Enzymes of this family are responsible for mRNA editing. They introduce base exchanges before the protein is translated, which plays an important role in defense of viral infections and lipid metabolism.
Genetests:
Related Diseases:
References:
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Vartanian JP et al. (2008) Evidence for editing of human papillomavirus DNA by APOBEC3 in benign and precancerous lesions.
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2. |
OhAinle M et al. (2006) Adaptive evolution and antiviral activity of the conserved mammalian cytidine deaminase APOBEC3H.
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3. |
Wedekind JE et al. (2003) Messenger RNA editing in mammals: new members of the APOBEC family seeking roles in the family business.
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4. |
NCBI article
NCBI 164668
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5. |
OMIM.ORG article
Omim 610976
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6. |
Wikipedia article
Wikipedia EN (APOBEC3H)
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Update: Aug. 14, 2020