Membrane cofactor protein

Bora NS et al. (1989) Structural gene for human membrane cofactor protein (MCP) of complement maps to within 100 kb of the 3' end of the C3b/C4b receptor gene.

Post TW et al. (1991) Membrane cofactor protein of the complement system: alternative splicing of serine/threonine/proline-rich exons and cytoplasmic tails produces multiple isoforms that correlate with protein phenotype.

Oliaro J et al. (2006) Ligation of the cell surface receptor, CD46, alters T cell polarity and response to antigen presentation.

Karosi T et al. (2008) Disease-associated novel CD46 splicing variants and pathologic bone remodeling in otosclerosis.

Yanagi Y et al. (2009) Measles virus receptors.

Kemper C et al. (2009) Measles virus and CD46.

Purcell DF et al. (1991) Identification of four different CD46 (MCP) molecules with anti-peptide antibodies.

Santiago C et al. (2010) Structure of the measles virus hemagglutinin bound to the CD46 receptor.

Haralambieva IH et al. (2011) Genetic polymorphisms in host antiviral genes: associations with humoral and cellular immunity to measles vaccine.

Ovsyannikova IG et al. (2011) The association of CD46, SLAM and CD209 cellular receptor gene SNPs with variations in measles vaccine-induced immune responses: a replication study and examination of novel polymorphisms.

Andrews PW et al. (1985) A human cell-surface antigen defined by a monoclonal antibody and controlled by a gene on human chromosome 1.

Nürnberger J et al. (2009) Eculizumab for atypical hemolytic-uremic syndrome.

Lublin DM et al. (1988) Molecular cloning and chromosomal localization of human membrane cofactor protein (MCP). Evidence for inclusion in the multigene family of complement-regulatory proteins.

Pirson Y et al. (1987) Hemolytic uremic syndrome in three adult siblings: a familial study and evolution.

McIntyre JA et al. (1983) Human trophoblast-lymphocyte cross-reactive (TLX) antigens define a new alloantigen system.

Cui W et al. (1993) Characterization of the promoter region of the membrane cofactor protein (CD46) gene of the human complement system and comparison to a membrane cofactor protein-like genetic element.

Dörig RE et al. (1993) The human CD46 molecule is a receptor for measles virus (Edmonston strain).

Källström H et al. (1997) Membrane cofactor protein (MCP or CD46) is a cellular pilus receptor for pathogenic Neisseria.

Goodship TH et al. (2004) Mutations in CD46, a complement regulatory protein, predispose to atypical HUS.

Richards A et al. (2007) Implications of the initial mutations in membrane cofactor protein (MCP; CD46) leading to atypical hemolytic uremic syndrome.

Zheng XL et al. (2008) Pathogenesis of thrombotic microangiopathies.

Caprioli J et al. (2006) Genetics of HUS: the impact of MCP, CFH, and IF mutations on clinical presentation, response to treatment, and outcome.

Xiang L et al. (1999) Quantitative alleles of CR1: coding sequence analysis and comparison of haplotypes in two ethnic groups.

Warwicker P et al. (1998) Genetic studies into inherited and sporadic hemolytic uremic syndrome.

Santoro F et al. (1999) CD46 is a cellular receptor for human herpesvirus 6.

Tatsuo H et al. (2000) SLAM (CDw150) is a cellular receptor for measles virus.

Källström H et al. (2001) Attachment of Neisseria gonorrhoeae to the cellular pilus receptor CD46: identification of domains important for bacterial adherence.

Marie JC et al. (2002) Linking innate and acquired immunity: divergent role of CD46 cytoplasmic domains in T cell induced inflammation.

Kemper C et al. (2003) Activation of human CD4+ cells with CD3 and CD46 induces a T-regulatory cell 1 phenotype.

Schneider-Schaulies J et al. (2003) Measles infection of the central nervous system.

Johansson L et al. (2003) CD46 in meningococcal disease.

Richards A et al. (2003) Mutations in human complement regulator, membrane cofactor protein (CD46), predispose to development of familial hemolytic uremic syndrome.

Gaggar A et al. (2003) CD46 is a cellular receptor for group B adenoviruses.

Noris M et al. (2003) Familial haemolytic uraemic syndrome and an MCP mutation.

Esparza-Gordillo J et al. (2005) Predisposition to atypical hemolytic uremic syndrome involves the concurrence of different susceptibility alleles in the regulators of complement activation gene cluster in 1q32.

Fremeaux-Bacchi V et al. (2005) The development of atypical haemolytic-uraemic syndrome is influenced by susceptibility factors in factor H and membrane cofactor protein: evidence from two independent cohorts.

Gaggar A et al. (2005) Localization of regions in CD46 that interact with adenovirus.

Cassiani-Ingoni R et al. (2005) CD46 on glial cells can function as a receptor for viral glycoprotein-mediated cell-cell fusion.

Yanagi Y et al. (2006) Measles virus receptors and tropism.

Tishon A et al. (2006) CD4 T cell control primary measles virus infection of the CNS: regulation is dependent on combined activity with either CD8 T cells or with B cells: CD4, CD8 or B cells alone are ineffective.

Sood R et al. (2006) Gene expression patterns in human placenta.

Yanagi Y et al. (2006) Measles virus: cellular receptors, tropism and pathogenesis.

OMIM.ORG article

Orphanet article

NCBI article

Wikipedia article