The disposition to develop hight triglyceride levels is hereditary. Among others, the gene ANGPTL4 is responsible.
Hypertriglyceridemia | ||||
APOA5 | ||||
APOE | ||||
Combined lipase deficiency | ||||
GPIHBP1 | ||||
LIPC | ||||
LIPE | ||||
LPL | ||||
Plasma triglyceride level quantitative trait locus | ||||
ANGPTL4 | ||||
Transient infantile hypertriglyceridemia | ||||
1. |
Romeo S et al. (2009) Rare loss-of-function mutations in ANGPTL family members contribute to plasma triglyceride levels in humans. |
2. |
Dewey FE et al. (2016) Inactivating Variants in ANGPTL4 and Risk of Coronary Artery Disease. |
3. |
et al. (2016) Coding Variation in ANGPTL4, LPL, and SVEP1 and the Risk of Coronary Disease. |
4. |
OMIM.ORG article Omim 615881 |