Open angle glaucoma 1E is an autosomal dominant disorder caused by mutations of the OPTN gene.
1. |
Gherghel D et al. (2005) Systemic reduction in glutathione levels occurs in patients with primary open-angle glaucoma. |
2. |
Harwerth RS et al. (1999) Ganglion cell losses underlying visual field defects from experimental glaucoma. |
3. |
Leung YF et al. (2000) Absence of trabecular meshwork-inducible stretch response (TISR)/oculomedin gene and proximal promoter mutation in primary open angle glaucoma patients. |
4. |
Yang J et al. (2001) T cell subsets and sIL-2R/IL-2 levels in patients with glaucoma. |
5. |
Nemesure B et al. (2003) A genome-wide scan for primary open-angle glaucoma (POAG): the Barbados Family Study of Open-Angle Glaucoma. |
6. |
Klein BE et al. (2004) Heritability of risk factors for primary open-angle glaucoma: the Beaver Dam Eye Study. |
7. |
Chauhan BC et al. (2004) Model of endothelin-1-induced chronic optic neuropathy in rat. |
8. |
Gottanka J et al. (2004) Effects of TGF-beta2 in perfused human eyes. |
9. |
Ferreira SM et al. (2004) Oxidative stress markers in aqueous humor of glaucoma patients. |
10. |
Tanito M et al. (2004) Reduction of posterior pole retinal thickness in glaucoma detected using the Retinal Thickness Analyzer. |
11. |
Sarfarazi M et al. (1998) Localization of the fourth locus (GLC1E) for adult-onset primary open-angle glaucoma to the 10p15-p14 region. |
12. |
Wang L et al. (2006) Endothelin B receptor in human glaucoma and experimentally induced optic nerve damage. |
13. |
Xu L et al. (2007) High myopia and glaucoma susceptibility the Beijing Eye Study. |
14. |
Polak K et al. (2007) Altered nitric oxide system in patients with open-angle glaucoma. |
15. |
Hewitt AW et al. (2007) Heritable features of the optic disc: a novel twin method for determining genetic significance. |
16. |
Johnson EC et al. (2007) Global changes in optic nerve head gene expression after exposure to elevated intraocular pressure in a rat glaucoma model. |
17. |
Xue W et al. (2007) Presence of an established calcification marker in trabecular meshwork tissue of glaucoma donors. |
18. |
Bahler CK et al. (2008) Prostaglandins increase trabecular meshwork outflow facility in cultured human anterior segments. |
19. |
Burdon KP et al. (2011) Genome-wide association study identifies susceptibility loci for open angle glaucoma at TMCO1 and CDKN2B-AS1. |
20. |
Borrás T et al. (2015) Prevention of nocturnal elevation of intraocular pressure by gene transfer of dominant-negative RhoA in rats. |
21. |
None (1997) Recent advances in molecular genetics of glaucomas. |
22. |
Wordinger RJ et al. (2007) Effects of TGF-beta2, BMP-4, and gremlin in the trabecular meshwork: implications for glaucoma. |
23. |
Rezaie T et al. (2002) Adult-onset primary open-angle glaucoma caused by mutations in optineurin. |
24. |
Chalasani ML et al. (2007) A glaucoma-associated mutant of optineurin selectively induces death of retinal ganglion cells which is inhibited by antioxidants. |
25. |
Wiggs JL et al. (2000) Genome-wide scan for adult onset primary open angle glaucoma. |
26. |
Wiggs JL et al. (1996) The distinction between juvenile and adult-onset primary open-angle glaucoma. |
27. |
None (1965) THE INHERITANCE OF GLAUCOMA. A PEDIGREE OF FAMILIAL GLAUCOMA. |
28. |
Wiggs JL et al. (2004) A genomewide scan identifies novel early-onset primary open-angle glaucoma loci on 9q22 and 20p12. |
29. |
None (1978) Current concepts in ophthalmology: the glaucomas. |
30. |
Southren AL et al. (1985) Genetic defect in cortisol metabolism in primary open angle glaucoma. |
31. |
Schwartz JT et al. (1972) Twin heritability study of the effect of corticosteroids on intraocular pressure. |
32. |
Armaly MF et al. (1968) Ocular pressure and aqueous outflow facility in siblings. |
33. |
None (1966) The heritable nature of dexamethasone-induced ocular hypertension. |
34. |
Coulehan JL et al. (1980) Racial differences in intraocular tension and glaucoma surgery. |
35. |
Quigley HA et al. (1994) Risk factors for the development of glaucomatous visual field loss in ocular hypertension. |
36. |
None (1993) Open-angle glaucoma. |
37. |
Quigley HA et al. (1997) Models of open-angle glaucoma prevalence and incidence in the United States. |
38. |
None (1997) Molecular genetics of the glaucomas: mapping of the first five "GLC" loci. |
39. |
Allingham RR et al. () Adult-onset primary open angle glaucoma does not localize to chromosome 2cen-q13 in North American families. |
40. |
OMIM.ORG article Omim 137760 |