Porokeratosis 3 is a rare autosomal dominant skin disorder caused by mutations of the MVK gene. The skinleasions are typically annular plaques with a keratotic brim. They spread centrifugally. They first appear on sun-exposed skin with adolescent age.
Mevalonate kinase-associated inflammatory diseases | ||||
Hyper-IgD syndrome | ||||
Mevalonic aciduria | ||||
Porokeratosis 3 | ||||
MVK | ||||
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16. |
Zhang Z et al. (2004) Fine mapping and identification of a candidate gene SSH1 in disseminated superficial actinic porokeratosis. |
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22. |
Orphanet article Orphanet ID 79358 |
23. |
OMIM.ORG article Omim 175900 |