Hypoaldosteronism is characterized by low aldosterone levels and the accompanying typical clinical symptoms, such as hypotension, water depletion, and hyperkalemia. Only loss-of-function mutations of the aldosteron synthase cause solely hypoaldosteronism. Often disturbances are more complex and different steroid hormone systems are affected.
Disorder of the aldosterone system | ||||
Hyperaldosteronism | ||||
Hypoaldosteronism | ||||
CYP11B2 | ||||
Pseudohyperaldosteronism | ||||
Pseudohypoaldosteronism | ||||
1. |
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10. |
OMIM.ORG article Omim 606984 |
11. |
Orphanet article Orphanet ID 171871 |
12. |
Wikipedia article Wikipedia EN (Hypoaldosteronism) |