Generalized lipodystrophy
Generalized lipodystrophy is characterized by reduction of adipose tissue throughout the body.
Acanthosis nigricans | |
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Generalized lipodystrophy is accompanied by acanthosis nigricans. |
Systematic
References:
1. |
None (2004) Acquired and inherited lipodystrophies. [^] |
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None (1946) Lipodystrophy and hepatomegaly, with diabetes, lipaemia, and other metabolic disturbances; a case throwing new light on the action of insulin. [^] |
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Shimomura I et al. (1998) Insulin resistance and diabetes mellitus in transgenic mice expressing nuclear SREBP-1c in adipose tissue: model for congenital generalized lipodystrophy. [^] |
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Agarwal AK et al. (2002) AGPAT2 is mutated in congenital generalized lipodystrophy linked to chromosome 9q34. [^] |
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None (1959) Lipodystrophy and gigantism with associated endocrine manifestations. A new diencephalic syndrome? [^] |
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Ebihara K et al. (2007) Efficacy and safety of leptin-replacement therapy and possible mechanisms of leptin actions in patients with generalized lipodystrophy. [^] |
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Kim CA et al. (2008) Association of a homozygous nonsense caveolin-1 mutation with Berardinelli-Seip congenital lipodystrophy. [^] |
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Simha V et al. (2008) Novel subtype of congenital generalized lipodystrophy associated with muscular weakness and cervical spine instability. [^] |
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Liu L et al. (2008) Deletion of Cavin/PTRF causes global loss of caveolae, dyslipidemia, and glucose intolerance. [^] |
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26. |
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Huseman CA et al. (1979) Congenital lipodystrophy. II. Association with polycystic ovarian disease. [^] |
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Brunzell JD et al. (1968) Congenital generalized lipodystrophy accompanied by cystic angiomatosis. [^] |
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None (1993) Percussion myoedema in a Pakistani boy with Berardinelli Seip lipodystrophy syndrome. [^] |
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OMIM.ORG article Omim 608594 [^] |
38. |
Orphanet article Orphanet ID 435628 [^] |
39. |
Wikipedia article Wikipedia EN (Congenital_generalized_lipodystrophy) [^] |