Laboratory for Molecular Diagnostics
Center for Nephrology and Metabolic Disorders

IgA nephropathy

IgA nephropathy is the most common type of glomerulonephritis characterized by typical immonohistochemical findings (IgA). Also, elevated levesl of IgA are found in patient's serum.

Systematic

Mesangioproliferative glomerulonephritis
CXCR1
Complement component C1q deficiency
IgA nephropathy
CFHR1
CFHR3
CFHR5
IgA nephropathy type 1
IgA nephropathy type 2
IgA nephropathy type 3
SPRY2
Schimke Immunoosseous dysplasia
Wiskott–Aldrich syndrome

References:

1.

Pei Y et al. (1997) Association of angiotensinogen gene T235 variant with progression of immunoglobin A nephropathy in Caucasian patients.

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2.

Yoshida H et al. (1995) Role of the deletion of polymorphism of the angiotensin converting enzyme gene in the progression and therapeutic responsiveness of IgA nephropathy.

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3.

Scolari F et al. (1999) Familial clustering of IgA nephropathy: further evidence in an Italian population.

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4.

Segerer S et al. (1999) Expression of the C-C chemokine receptor 5 in human kidney diseases.

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5.

Zheng F et al. (1999) Uteroglobin is essential in preventing immunoglobulin A nephropathy in mice.

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6.

Hsu SI et al. (2000) Evidence for genetic factors in the development and progression of IgA nephropathy.

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7.

Gharavi AG et al. (2000) IgA nephropathy, the most common cause of glomerulonephritis, is linked to 6q22-23.

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8.

Hiki Y et al. (2001) Mass spectrometry proves under-O-glycosylation of glomerular IgA1 in IgA nephropathy.

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9.

Allen AC et al. (2001) Mesangial IgA1 in IgA nephropathy exhibits aberrant O-glycosylation: observations in three patients.

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10.

Takei T et al. (2002) Association between single-nucleotide polymorphisms in selectin genes and immunoglobulin A nephropathy.

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11.

Donadio JV et al. (2002) IgA nephropathy.

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12.

Yoon HJ et al. (2003) Association of the CD14 gene -159C polymorphism with progression of IgA nephropathy.

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13.

Song J et al. (2003) Gender specific association of aldosterone synthase gene polymorphism with renal survival in patients with IgA nephropathy.

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14.

Wang J et al. (2004) Dysregulated LIGHT expression on T cells mediates intestinal inflammation and contributes to IgA nephropathy.

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15.

Bisceglia L et al. (2006) Genetic heterogeneity in Italian families with IgA nephropathy: suggestive linkage for two novel IgA nephropathy loci.

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16.

Suzuki H et al. (2008) IgA1-secreting cell lines from patients with IgA nephropathy produce aberrantly glycosylated IgA1.

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17.

None (1989) Familial cases of Berger's disease and anaphylactoid purpura: more frequent than previously thought.

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18.

None (1987) The commonest glomerulonephritis in the world: IgA nephropathy.

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19.

Julian BA et al. (1988) IgA nephropathy, the most common glomerulonephritis worldwide. A neglected disease in the United States?

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20.

Asamoah A et al. (1987) A major gene model for the familial aggregation of plasma IgA concentration.

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21.

Coppo R et al. (1986) Dietary gluten and primary IgA nephropathy.

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22.

Julian BA et al. (1985) Familial IgA nephropathy. Evidence of an inherited mechanism of disease.

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23.

Jennette JC et al. (1985) Low incidence of IgA nephropathy in blacks.

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24.

None (1969) IgA glomerular deposits in renal disease.

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25.

Sabatier JC et al. (1979) Mesangial IgA glomerulonephritis in HLA-identical brothers.

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26.

McCoy RC et al. (1974) IgA nephropathy.

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27.

Croker BP et al. (1983) IgA nephropathy. Correlation of clinical and histologic features.

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28.

Bene MC et al. (1983) Immunoglobulin A nephropathy. Quantitative immunohistomorphometry of the tonsillar plasma cells evidences an inversion of the immunoglobulin A versus immunoglobulin G secreting cell balance.

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29.

Berthoux FC et al. (1978) HLA-Bw35 and mesangial IgA glomerulonephritis.

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30.

Brettle R et al. (1978) Mesangial IgA glomerulonephritis and HLA antigens.

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31.

Tolkoff-Rubin NE et al. (1978) IGA nephropathy in HLA-identical siblings.

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32.

Katz A et al. (1980) Family study in IgA nephritis: the possible role of HLA antigens.

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33.

Tomana M et al. (1997) Galactose-deficient IgA1 in sera of IgA nephropathy patients is present in complexes with IgG.

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34.

OMIM.ORG article

Omim 161950 [^]
35.

Wikipedia article

Wikipedia EN (IgA_nephropathy) [^]
Update: May 10, 2019