Transient neonatal diabetes mellitus 2
Transient neonatal diabetes mellitus is an autosomal dominant disorder caused by mutations of the ABCC8 gene. The clinical variation within a family can vary significantly from transient or permanent neonatal diabetes mellitus to a typical type 2 diabetes of adulthood.
The disease is cause by an activating mutation of the ABCC8 gene.
The disease can be treated by sulfonyl urea.
Babenko AP et al. (2006) Activating mutations in the ABCC8 gene in neonatal diabetes mellitus.[^]
OMIM.ORG articleOmim 610374 [^]