Laboratory for Molecular Diagnostics
Center for Nephrology and Metabolic Disorders
Glomerulosclerosis describes histomorphological alterations of the kidney characterized by glomerular fibrosis and scars. This is the common end point in several pathological processes affecting the glomerulus. It may occur focal, only some glomeruli altered, and segmental, only parts of the glomerulus affected.
Proteinuria, glomerular haematuria, and progressive decline of renal function are the dominating clinical symptoms, which start in teenage years and may develop to end-stage renal disease in some individuals.
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Orphanet article Orphanet ID 93218
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Wikipedia article Wikipedia EN (Glomerulosclerosis)
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