Laboratory for Molecular Diagnostics
Center for Nephrology and Metabolic Disorders

MODY4 diabetes

MODY4 is an autosomal dominant early-onset type 2 diabetes caused by mutations of the PDX1 gene.

Test Strategy

Diagnostic criteria are explained on general MODY page.

Systematic

MODY diabetes
MODY1 diabetes
MODY10 diabetes
MODY11 diabetes
MODY12 diabetes
MODY13 diabetes
MODY14 diabetes
MODY2 diabetes
MODY3 diabetes
MODY4 diabetes
PDX1
MODY5 diabetes
MODY6 diabetes
MODY7 diabetes
MODY8 diabetes
MODY9 diabetes

References:

1.

Fajans SS et al. (2001) Molecular mechanisms and clinical pathophysiology of maturity-onset diabetes of the young.

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2.

Weng J et al. (2002) Screening for MODY mutations, GAD antibodies, and type 1 diabetes--associated HLA genotypes in women with gestational diabetes mellitus.

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3.

Weng J et al. (2001) Functional consequences of mutations in the MODY4 gene (IPF1) and coexistence with MODY3 mutations.

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4.

OMIM.ORG article

Omim 606392 [^]
Update: May 9, 2019