Molekulargenetische Diagnostik
Praxis Dr. Mato Nagel

C-X-C Chemokin-Rezeptor Typ 1

IL-8-Rezeptor Typ 1; Interleukin 8-Rezeptor 1

Diagnostik:

Clinic Untersuchungsmethoden Familienuntersuchung
Bearbeitungszeit 5
Probentyp genomic DNA
Research Untersuchungsmethoden Direkte Sequenzierung der proteinkodierenden Bereiche eines Gens
Bearbeitungszeit 25
Probentyp genomic DNA
Clinic Untersuchungsmethoden Hochdurchsatz-Sequenzierung
Bearbeitungszeit 25
Probentyp genomic DNA

Krankheiten:

HIV-Resistenz
CCR5
CXCR1
Mesangioproliferative Glomerulonephritis
CXCR1
IgA-Nephropathie
CFHR1
CFHR3
CFHR5
IgA-Nephropathie Typ 1
IgA-Nephropathie Typ 2
IgA-Nephropathie Typ 3
SPRY2
Komplement C1q-Mangel
C1QA
C1QB
C1QC
Schimke-Dysplasie
SMARCAL1
Wiskott-Aldrich-Syndrom
WAS

Referenzen:

1.

Morris SW et. al. (1992) Assignment of the genes encoding human interleukin-8 receptor types 1 and 2 and an interleukin-8 receptor pseudogene to chromosome 2q35.

[^]
2.

Holmes WE et. al. (1991) Structure and functional expression of a human interleukin-8 receptor.

[^]
3.

Mollereau C et. al. (1993) The high-affinity interleukin 8 receptor gene (IL8RA) maps to the 2q33-q36 region of the human genome: cloning of a pseudogene (IL8RBP) for the low-affinity receptor.

[^]
4.

Lloyd A et. al. (1993) Assignment of genes for interleukin-8 receptors (IL8R) A and B to human chromosome band 2q35.

[^]
5.

Palter SF et. al. (2001) Interleukin-8 in the human fallopian tube.

[^]
6.

Weathington NM et. al. (2006) A novel peptide CXCR ligand derived from extracellular matrix degradation during airway inflammation.

[^]
7.

Vasilescu A et. al. (2007) A haplotype of the human CXCR1 gene protective against rapid disease progression in HIV-1+ patients.

[^]
8.

Hartl D et. al. (2007) Cleavage of CXCR1 on neutrophils disables bacterial killing in cystic fibrosis lung disease.

[^]
9.

Ozaltin F et. al. (2013) Role of CXCR1 (CKR-1) in inflammation of experimental mesangioproliferative glomerulonephritis.

[^]

 

 
Ihre Nachricht: