Molekulargenetische Diagnostik
Praxis Dr. Mato Nagel

Veranlagung für entzündliche Darmerkrankungen 13

Die Veranlagung für entzündliche Darmerkrankungen kann vererbt werden. Für den Typ 13 ist das Gen ABCB1 verantwortlich.

Gliederung

Veranlagung für entzündliche Darmerkrankungen
SEL1L
Veranlagung für entzündliche Darmerkrankungen 13
ABCB1

Referenzen:

1.

Panwala CM et. al. (1998) A novel model of inflammatory bowel disease: mice deficient for the multiple drug resistance gene, mdr1a, spontaneously develop colitis.

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2.

Brant SR et. al. (2003) MDR1 Ala893 polymorphism is associated with inflammatory bowel disease.

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3.

Ho GT et. al. (2006) ABCB1/MDR1 gene determines susceptibility and phenotype in ulcerative colitis: discrimination of critical variants using a gene-wide haplotype tagging approach.

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4.

Satsangi J et. al. (1996) Two stage genome-wide search in inflammatory bowel disease provides evidence for susceptibility loci on chromosomes 3, 7 and 12.

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5.

Cho JH et. al. (1998) Identification of novel susceptibility loci for inflammatory bowel disease on chromosomes 1p, 3q, and 4q: evidence for epistasis between 1p and IBD1.

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6.

Kim RB et. al. (2001) Identification of functionally variant MDR1 alleles among European Americans and African Americans.

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