Molekulargenetische Diagnostik
Praxis Dr. Mato Nagel

Weitwinkelglaukom 1E

Das Weitwinkelglaukom 1E ist eine autosomal dominante Erkrankung, die durch Mutationen im OPTN-Gen ausgelöst wird.

Gliederung

Weitwinkelglaukom 1
Weitwinkelglaukom 1A
Weitwinkelglaukom 1B
Weitwinkelglaukom 1C
Weitwinkelglaukom 1D
Weitwinkelglaukom 1E
OPTN
Weitwinkelglaukom 1F
Weitwinkelglaukom 1G
Weitwinkelglaukom 1H
Weitwinkelglaukom 1I
Weitwinkelglaukom 1J
Weitwinkelglaukom 1K
Weitwinkelglaukom 1L
Weitwinkelglaukom 1M
Weitwinkelglaukom 1N
Weitwinkelglaukom 1O
Weitwinkelglaukom 1P

Referenzen:

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2.

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3.

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4.

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5.

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6.

None (1965) THE INHERITANCE OF GLAUCOMA. A PEDIGREE OF FAMILIAL GLAUCOMA.

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7.

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8.

None (1978) Current concepts in ophthalmology: the glaucomas.

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9.

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10.

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11.

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12.

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13.

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14.

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15.

None (1993) Open-angle glaucoma.

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16.

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17.

None (1997) Molecular genetics of the glaucomas: mapping of the first five "GLC" loci.

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18.

None (1997) Recent advances in molecular genetics of glaucomas.

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19.

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20.

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21.

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22.

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24.

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25.

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26.

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27.

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28.

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29.

Gherghel D et. al. (2005) Systemic reduction in glutathione levels occurs in patients with primary open-angle glaucoma.

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30.

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31.

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32.

Wordinger RJ et. al. (2007) Effects of TGF-beta2, BMP-4, and gremlin in the trabecular meshwork: implications for glaucoma.

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33.

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34.

Hewitt AW et. al. (2007) Heritable features of the optic disc: a novel twin method for determining genetic significance.

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35.

Johnson EC et. al. (2007) Global changes in optic nerve head gene expression after exposure to elevated intraocular pressure in a rat glaucoma model.

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36.

Xue W et. al. (2007) Presence of an established calcification marker in trabecular meshwork tissue of glaucoma donors.

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37.

Bahler CK et. al. (2008) Prostaglandins increase trabecular meshwork outflow facility in cultured human anterior segments.

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38.

Burdon KP et. al. (2011) Genome-wide association study identifies susceptibility loci for open angle glaucoma at TMCO1 and CDKN2B-AS1.

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39.

Borrás T et. al. (2015) Prevention of nocturnal elevation of intraocular pressure by gene transfer of dominant-negative RhoA in rats.

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