Als Komplement C8-Mangel Typ 2 wird eine Mangel der beta-Untereinheit des Proteins verstanden. Klinisch lässt sich der Typ 2 vom Typ 1 (alpha-Untereinheit betreffend) nicht unterscheiden. Beide Typen sind für eine gestörte Abwehr insbesondere von Meningokokken-Infektionen verantwortlich.
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OMIM.ORG article Omim 613789 |