Calcinosis is the calcification (calcium deposition) in soft tissues that is outside the bones.
Calcinosis can be caused by local or systemic factors. The former are injuries or injections; the latter hyperparathyroidism or disorders of calcium and phosphate metabolism.
Several forms of Calcinosis can can be clinically distinguished:
- c. circumscripta
- c. cutis
- c. intervertebralis calcification of nucleus pulposus (often) and anulus fibrosis (rare) of one or many intervertebral disks.
- tumoral c. sometimes large soft tissue calcifications around big joints like shoulder, elbow, and hip. Symptoms are mainly caused by nerve compression.
- c. universalis
- c. metastatica
- c. interstitialis
|Hyperphosphatemic familial tumoral calcinosis|
Calcinosis tumoralis is caused by prolonged hyperphosphatemia.