Laboratory for Molecular Diagnostics
Center for Nephrology and Metabolic Disorders


Virilization is the change of an individual's physical appearance to a more male type. This change, also called sexual dimorphism, happens under the influence if male sex hormones (androgens).


Glucocorticoid resistance
Hyperandrogenism causes virilization in females in whom most of the androgens are produced ACTH-dependently by the adrenals. As in in men the androgen production is predominantly maintained by the testes adrenal hyperandrogenism has no clinical effect.
Update: April 29, 2019