Laboratory for Molecular Diagnostics
Center for Nephrology and Metabolic Disorders
Heterotopic Ossification is the formation of bone like tissues outside the skeleton, predominantly in connective tissues.
| Albright hereditary osteodystrophy | |
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In Albright hereditary osteodystrophy (AHO) subcutaneous ossifications are accompanied by hormone resistance and dysmorphic features. |
| Fibrodysplasia ossificans progressiva | |
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In fibrodysplasia Ossificans Progressiva (FOP) heterotopic bone formation is localized in tendons, ligaments, skeletal muscles and fascia. Before the appearance of bone like tissues tumor-like inflammation (“flare-ups”) is observed. |
| Progressive osseous heteroplasia | |
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With progressive osseous heteroplasia ossification starts in childhood with superficial dermal ossification. |
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