Laboratory for Molecular Diagnostics
Center for Nephrology and Metabolic Disorders

Acidosis

Acidosis is understood as an acid base disturbance with an initial decrease in blood pH. If this unsettling situation remains, the organism employs internal mechanisms to counteract, and although the pH might become normal again, the shift caused in the buffer system is still measurable.

Pathogenesis

Acidosis may be cause by pulmonary insufficiency - respiratory acidosis or the inability of bicoabonate production - metabolic acidosis.

Classification

In addition to the pathogenetic classification metabolic and respiratory forms of acidosis may further be compensated or not.

Diseases

Glucose-Galactose Malabsorption
Patients with glucose-galactose malabsorption may also show renal tubular acidosis based on proximal tubular damage.
Renal tubular acidosis
Hyperchloremic metabolic acidosis is the hallmark of RTA.
Update: June 23, 2016