Laboratory for Molecular Diagnostics
Center for Nephrology and Metabolic Disorders
Mutations of the ASB10 gene cause autosomal dominant open angle glaucoma 1F.
| Clinic | Method | Carrier testing |
| Turnaround | 5 days | |
| Specimen type | genomic DNA |
| Clinic | Method | Massive parallel sequencing |
| Turnaround | 25 days | |
| Specimen type | genomic DNA |
| Clinic | Method | Genomic sequencing of the entire coding region |
| Turnaround | 25 days | |
| Specimen type | genomic DNA |
| 1. |
Wirtz MK et al. (1999) GLC1F, a new primary open-angle glaucoma locus, maps to 7q35-q36. 
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| 2. |
Pasutto F et al. (2012) Variants in ASB10 are associated with open-angle glaucoma.
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| 3. |
Kile BT et al. (2001) Functional analysis of Asb-1 using genetic modification in mice.
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| 4. |
Kile BT et al. (2002) The SOCS box: a tale of destruction and degradation.
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| 5. |
NCBI article NCBI 136371
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| 6. |
OMIM.ORG article Omim 615054
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