Growth hormone releasing hormone
The protein encoded by this gene stimulates growth hormone release from the pituitary thru the releasing hormon receptor (GHRHR).
Genetests:
Related Diseases:
References:
1. |
Kiaris H et al. (1999) Growth hormone-releasing hormone: an autocrine growth factor for small cell lung carcinoma.
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Flavell DM et al. (1996) Dominant dwarfism in transgenic rats by targeting human growth hormone (GH) expression to hypothalamic GH-releasing factor neurons.
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3. |
Zimmerman D et al. (1993) Congenital gigantism due to growth hormone-releasing hormone excess and pituitary hyperplasia with adenomatous transformation.
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4. |
Pérez Jurado LA et al. (1994) Genetic mapping of the human growth hormone-releasing factor gene (GHRF) using two intragenic polymorphisms detected by PCR amplification.
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5. |
Scheithauer BW et al. (1984) Ectopic secretion of a growth hormone-releasing factor. Report of a case of acromegaly with bronchial carcinoid tumor.
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6. |
Thorner MO et al. (1982) Somatotroph hyperplasia. Successful treatment of acromegaly by removal of a pancreatic islet tumor secreting a growth hormone-releasing factor.
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7. |
Gubler U et al. (1983) Cloning and sequence analysis of cDNA for the precursor of human growth hormone-releasing factor, somatocrinin.
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8. |
Mayo KE et al. (1985) Gene encoding human growth hormone-releasing factor precursor: structure, sequence, and chromosomal assignment.
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9. |
Thorner MO et al. (1988) Acceleration of growth rate in growth hormone-deficient children treated with human growth hormone-releasing hormone.
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10. |
Ling N et al. (1985) Growth hormone releasing factors.
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11. |
Riddell DC et al. (1985) Chromosomal assignment of human sequences encoding arginine vasopressin-neurophysin II and growth hormone releasing factor.
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12. |
Mitrakou A et al. (1985) Heterogeneity of growth-hormone deficiency.
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13. |
Shohat M et al. (1991) Deletion of 20p 11.23----pter with normal growth hormone-releasing hormone genes.
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14. |
Rao VV et al. (1991) The gene for human growth hormone-releasing factor (GHRF) maps to or near chromosome 20p12.
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15. |
Kanashiro CA et al. (2003) Inhibition of mutant p53 expression and growth of DMS-153 small cell lung carcinoma by antagonists of growth hormone-releasing hormone and bombesin.
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16. |
Jessup SK et al. (2003) Sexual dimorphism of growth hormone (GH) regulation in humans: endogenous GH-releasing hormone maintains basal GH in women but not in men.
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17. |
Letsch M et al. (2003) Growth hormone-releasing hormone (GHRH) antagonists inhibit the proliferation of androgen-dependent and -independent prostate cancers.
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18. |
Halmos G et al. (2002) Expression of growth hormone-releasing hormone and its receptor splice variants in human prostate cancer.
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19. |
Busto R et al. (2002) The expression of growth hormone-releasing hormone (GHRH) and splice variants of its receptor in human gastroenteropancreatic carcinomas.
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20. |
Gianotti L et al. (2000) Arginine counteracts the inhibitory effect of recombinant human insulin-like growth factor I on the somatotroph responsiveness to growth hormone-releasing hormone in humans.
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21. |
Russell-Aulet M et al. (1999) In vivo semiquantification of hypothalamic growth hormone-releasing hormone (GHRH) output in humans: evidence for relative GHRH deficiency in aging.
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22. |
NCBI article
NCBI 2691
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23. |
OMIM.ORG article
Omim 139190
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24. |
Wikipedia article
Wikipedia EN (Growth_hormone–releasing_hormone)
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Update: Aug. 14, 2020