Laboratory for Molecular Diagnostics
Center for Nephrology and Metabolic Disorders
Moldiag Diseases Genes Support Contact

Hereditary papillary renal cell carcinoma 1

Familial papillary renal cell carcinoma type 1 is caused by mutations of the MET gene. The disorder is characterized by multifocal papillary renal carcinoma. Also somatic mutation are observed in sporadic cases.

Systematic

Hereditary papillary renal cell carcinoma
Hereditary papillary renal cell carcinoma 1
MET
PRCC

References:

1.

Zhuang Z et al. (1998) Trisomy 7-harbouring non-random duplication of the mutant MET allele in hereditary papillary renal carcinomas.

external link
2.

None (2011) Hereditary leiomyomatosis and renal cell cancer: update on clinical and molecular characteristics.

external link
3.

Yang XJ et al. (2005) A molecular classification of papillary renal cell carcinoma.

external link
4.

Kuroda N et al. (2003) Review of papillary renal cell carcinoma with focus on clinical and pathobiological aspects.

external link
5.

Balint I et al. (1999) Mapping the papillary renal cell carcinoma gene between loci D17S787 and D17S1799 on chromosome 17q21.32.

external link
6.

Fischer J et al. (1998) Duplication and overexpression of the mutant allele of the MET proto-oncogene in multiple hereditary papillary renal cell tumours.

external link
7.

Zbar B et al. (1994) Hereditary papillary renal cell carcinoma.

external link
8.

None (1993) Molecular cytogenetics of renal cell tumors.

external link
9.

Zbar B et al. (1995) Hereditary papillary renal cell carcinoma: clinical studies in 10 families.

external link
10.

Kovacs G et al. (1991) Cytogenetics of papillary renal cell tumors.

external link
11.

Mancilla-Jimenez R et al. (1976) Papillary renal cell carcinoma: a clinical, radiologic, and pathologic study of 34 cases.

external link
12.

Kovacs G et al. (1997) The Heidelberg classification of renal cell tumours.

external link
13.

Kuiper RP et al. (2003) Upregulation of the transcription factor TFEB in t(6;11)(p21;q13)-positive renal cell carcinomas due to promoter substitution.

external link
14.

Bodmer D et al. (2002) Understanding familial and non-familial renal cell cancer.

external link
15.

Cohen HT et al. (2005) Renal-cell carcinoma.

external link
16.

Cohen AJ et al. (1979) Hereditary renal-cell carcinoma associated with a chromosomal translocation.

external link
17.

Schmidt L et al. (1997) Germline and somatic mutations in the tyrosine kinase domain of the MET proto-oncogene in papillary renal carcinomas.

external link
18.

OMIM.ORG article

Omim 605074 external link
19.

Orphanet article

Orphanet ID 319298 external link
Update: Aug. 14, 2020
Copyright © 2005-2024 by Center for Nephrology and Metabolic Disorders, Dr. Mato Nagel, MD
Albert-Schweitzer-Ring 32, D-02943 Weißwasser, Germany, Tel.: +49-3576-287922, Fax: +49-3576-287944
Sitemap | Webmail | Disclaimer | Privacy Issues | Website Credits