Laboratory for Molecular Diagnostics
Center for Nephrology and Metabolic Disorders
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Inflammatory bowel disease 13

The disposition to develop inflammatory bowel disease is hereditary. For type 13, the gene ABCB1 is responsible.

Systematic

Inflammatory bowel disease
Crohn disease-associated growth failure
Inflammatory bowel disease 13
ABCB1
Inflammatory bowel disease 25
Inflammatory bowel disease 28
SEL1L

References:

1.

Panwala CM et al. (1998) A novel model of inflammatory bowel disease: mice deficient for the multiple drug resistance gene, mdr1a, spontaneously develop colitis.

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2.

Brant SR et al. (2003) MDR1 Ala893 polymorphism is associated with inflammatory bowel disease.

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3.

Ho GT et al. (2006) ABCB1/MDR1 gene determines susceptibility and phenotype in ulcerative colitis: discrimination of critical variants using a gene-wide haplotype tagging approach.

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4.

Satsangi J et al. (1996) Two stage genome-wide search in inflammatory bowel disease provides evidence for susceptibility loci on chromosomes 3, 7 and 12.

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5.

Cho JH et al. (1998) Identification of novel susceptibility loci for inflammatory bowel disease on chromosomes 1p, 3q, and 4q: evidence for epistasis between 1p and IBD1.

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6.

Kim RB et al. (2001) Identification of functionally variant MDR1 alleles among European Americans and African Americans.

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7.

OMIM.ORG article

Omim 612244 external link
Update: Aug. 14, 2020
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