Autoimmune polyendocrinopathy syndrome 2 is an autosomal dominant disorder linked to the HLA locus. The exact molecular cause of the disease remains to be clarified. The disease is characterised by an autoimmune adrenal insufficiency and additionally at least one of autoimmune thyroiditis or type 1 diabetes mellitus.
The frequency of the disease is about 1.4 to 4.5 per 100,000 individuals[Error: Macro 'ref' doesn't exist]
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Orphanet article Orphanet ID 85138 |
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Wikipedia article Wikipedia EN (Autoimmune_polyendocrine_syndrome_type_2) |