Hyper-IgM syndrome 5

Hyper-IgM syndrome 5 is an aautosomal recessiv disorder caused by mutations of the UNG gene. The disorder is characterized clinically by elevated immunoglobulin IgM levels that are meant to compensate a deficiency in IgG, IgA, and IgM.

Systematic

Hyper-IgM syndrome
	Hyper-IgM syndrome 1
	Hyper-IgM syndrome 2
	Hyper-IgM syndrome 3
	Hyper-IgM syndrome 4
	Hyper-IgM syndrome 5
		UNG

References:

1.	Imai K et al. (2003) Human uracil-DNA glycosylase deficiency associated with profoundly impaired immunoglobulin class-switch recombination.

2.	OMIM.ORG article Omim 608106